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NIH awards $21 million grant to study early stages of HIV-1 infection

LA JOLLA, CA-A multi-institutional team headed by John Young, Ph.D., a professor at the Salk Institute for Biological Studies, and Sumit Chanda, Ph.D., an associate professor at Sanford-Burnham Medical Research Institute, has been awarded a $21 million Program Project Grant to dissect the early innate immune response to HIV infection using a systems biology approach.
The project will bring together a multidisciplinary team that draws on the expertise of 13 research groups at seven institutions to uncover the cellular protein machinery that represents the first line of defense against HIV, the cause of AIDS.

Participating Researchers and Institutions

Salk Institute for Biological Studies
Dr. John Young (Principal Investigator/Program Director)

Sanford Burnham Medical Research Institute
Drs. Sumit Chanda (Program Deputy Director), John Reed, Renate Konig

University of California, San Francisco
Drs. Nevan Krogan, Leor Weinberger

Mount Sinai School of Medicine
Drs. Adolfo Garcia-Sastre, Ana Fernandez-Sesma, Viviana Simon

University of California, San Diego
Drs. Alexander Hoffmann, Michael David

Northwestern University
Dr. Steven Wolinsky

University of Pennsylvania
Dr. Frederic Bushman